WB D.Pharm Pharmaceutics Question Paper 2024: Analyze, Prepare, Excel!Decoding Diploma Dreams: The 2024 WB Pharmaceutics Question Paper
Ever wondered what the Pharmaceutics exam for the West Bengal Diploma in Pharmacy looked like last year? Here's your exclusive peek behind the curtain! Unveiling the 2024 question paper from the West Bengal Board, this post is your opportunity to get familiar with the exam's nuances and tailor your studies for maximum impact. Get ready to unlock the secrets to success in your Pharmaceutics examination!
PHARMACEUTICS
Time Allowed: 3 Hours Full Marks: 80
Fill up the blanks with appropriate word(s) (Any ten): 1x10
i) The first edition of IP was published in the year ______ .
ii) Methylparaben, propylparaben are examples of ______.
iii) Fibrous materials are size reduced by ______ mill.
iv) Triple roller mill is used for the preparation of ______.
v) Soxhlet apparatus is used in ______.
vi) Darcy's Law is associated with ______ .
vii) ______ is a manufacturing defect of a tablet.
viii) Example of Glidant in Tablet preparation is ______
ix) Enteric coated tablets disintegrate in ______.
x) The biggest capsule size is denoted by ______ .
xi) Ball mill works on the principle of ______ .
Write short note (Any ten): 1x10
a) Suppository
b) Mixture
c) BCG vaccine
d) Lyophilization
e) Emulsifying agents
f) GMP
g) Percolation
h) Uses of Cyclone separator
i) Ointments
j) LVP
k) Soda lime Glass
Short answer type questions (Any ten): 3x10
i) Discuss the advantages of granules compared to powder.
ii) Differentiate between Infusion & Maceration.
iii) What do you understand by dosage form? Classify.
iv) Differentiate between Active & Passive immunity.
v) Define preservatives. Classify Preservatives based on their mechanism of action.
vi) Discuss the factors affecting filtration.
vii) Discuss the ideal properties of packaging materials.
viii) Write a note on Soft Gelatin Capsule.
ix) What are the objectives of mixing?
x) Classify powder as per IP grade.
xi) Classify preservatives as per source, solubility, dosage form, food items, parenteral preparation, topical preparation etc.
Long answer type questions (Any six): 5x6
i) Define Extraction. Briefly discuss Maceration and Percolation. 1+2+2
ii) What do you mean by QC & QA? Differentiate between QC & QA.
2+3
iii) What is Immunity? Name different types of Immunity. What do you mean by "vaccine"? Name different types of vaccines with examples.
1+1+1+2
iv) Various steps involved in preparation of Sugar Coating Tablets.
v) Write about the working of the Fluid Bed Dryer.
vi) Flow chart of Steps involved in wet granulation tablet preparation.
vii) Discuss the advantages of Capsule. Differentiate between hard gelatin and soft gelatin capsules.
ANSWER
1. Fill up the blanks with appropriate word(s) (Any ten): (1x10 = 10 Marks)
i) The first edition of IP was published in the year 1955.
ii) Methylparaben, propylparaben are examples of preservatives.
iii) Fibrous materials are size reduced by hammer mill.
iv) Triple roller mill is used for the preparation of ointments/pastes.
v) Soxhlet apparatus is used in extraction.
vi) Darcy's Law is associated with rate of filtration.
vii) Capping/Lamination is a manufacturing defect of a tablet.
viii) Example of Glidant in Tablet preparation is talc/colloidal silicon dioxide.
ix) Enteric coated tablets disintegrate in intestinal fluid/alkaline pH.
x) The biggest capsule size is denoted by 000.
xi) Ball mill works on the principle of impact and attrition.
2. Write short note (Any ten): (1x10 = 10 Marks)
(a) Suppository: Solid or semi-solid dosage form intended for insertion into body orifices like the rectum, vagina, or urethra, where they melt, soften, or dissolve to release the drug for local or systemic effect.
(b) Mixture: A liquid pharmaceutical preparation containing one or more medicinal agents dissolved or dispersed in a suitable vehicle. Mixtures are usually intended for oral administration.
(c) BCG vaccine: Bacillus Calmette-Guérin vaccine is a live attenuated vaccine prepared from Mycobacterium bovis. It is primarily used for vaccination against tuberculosis.
(d) Lyophilization: Also known as freeze-drying, it's a process used to remove water from a product, typically unstable biologicals, to preserve it. It involves freezing the product and then reducing the surrounding pressure to allow the frozen water to sublimate directly from the solid phase to the gas phase.
(e) Emulsifying agents: Substances that promote and maintain the formation of an emulsion, a stable mixture of two or more immiscible liquids. They work by reducing the interfacial tension between the liquids and forming a protective barrier around the dispersed globules.
(f) GMP: Good Manufacturing Practice is a system for ensuring that products are consistently produced and controlled according to quality standards. It covers all aspects of production from starting materials, premises and equipment to the training and personal hygiene of staff.
(g) Percolation: A solid-liquid extraction process where the powdered drug is packed in a percolator, and the solvent (menstruum) is allowed to slowly pass through the bed of drug, extracting the soluble constituents.
(h) Uses of Cyclone separator: A device used to remove particulate matter from air, gas, or liquid streams without the use of filters, through vortex separation. In pharmaceuticals, it's used for dust collection and particle size separation.
(i) Ointments: Semi-solid preparations intended for external application to the skin or mucous membranes. They usually consist of a medicament dissolved or dispersed in a suitable greasy base.
(j) LVP: Large Volume Parenteral are sterile, pyrogen-free solutions intended for intravenous infusion in volumes of 100 mL or more. Examples include saline solutions, dextrose solutions, and electrolyte solutions.
(k) Soda lime Glass: A type of glass composed mainly of silica, sodium carbonate, and calcium carbonate. It is commonly used for making glass containers for pharmaceuticals due to its relatively low cost and chemical durability.
